Onchocerciasis, also known as river blindness, is an infectious disease that is caused by the parasitic worm Onchocerca volvulus. The infection is transmitted by Simulium blackflies through a bite. It is the second leading infectious disease that results in vision loss. Unlike other diseases, this disease requires repeated bites for an infection to happen. The disease is also called river blindness because the fly breeds in streams and rivers and leads to vision loss. Onchocerciasis is prevailing in remote rural areas which makes those who live or work in these areas more at risk.